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Phentermine alone produces approximately 5-8% body weight loss over 12 weeks in responders, but benefits plateau as tolerance develops

The second tier is rare but serious : a sudden loss of vision in one eye, which can signal an optic-nerve problem

Yet there is currently only one FDA-approved adjunctive therapy for type 1: Symlin (pramlintide), a drug that is rarely used due to its long list of side effects

Tirzepatide can sometimes cause slightly stronger early side effects because of its dual action, but this depends heavily on individual tolerance and dose titration

"We started to be able to use this, and started to see an effect in our patients, where they were losing up to about 14% of their body weight, which was more than what we had seen prior." Wegovy and Ozempic (FOX 5) Shelly says both drugs work by slowing down how quickly food moves through the digestive tract