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In the male offspring, increased fission markers and reduced autophagosome markers at P1 suggesting an increase in mitochondrial damage and thereby overconsumption of the autophagosome, while data from adult offspring suggest reduced mitophagy but increased cellular damage

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Publication "Safety of GLP-1 receptor agonists and other 2nd-line antidiabetics in early pregnancy: an international cohort study, Carolyn E

When stored at 2 to 8 degrees Celsius (36 to 46 degrees Fahrenheit) , they remain potent until the printed expiration date, which is usually about 24 months from manufacture