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& Al-Hasawi, F

The mice were euthanized by cervical dislocation and the spleen was weighed to calculate the spleen index: spleen index = spleen weight (g)/mouse weight (g)

(2014) 306:H36372

These target genes encompass a wide range of antioxidant enzymes and GSH synthesis-related genes, including the key System Xc component SLC7A11

CD4 + T-cell subsets, T-helper 17 (Th17), and regulatory T cells (Treg) play a vital role by limiting -synuclein-mediated microglial activation and reducing the activity of CD8 + cytotoxic T-cell and natural killer (NK) cells during the neuroinflammation processes in PD ( + T-cell infiltration in the substantia nigra pars compacta was observed in the brain in early pre-symptomatic PD, which correlated with -synuclein aggregate accumulation and eventual dopaminergic neuronal cell loss ( + T-cell subsets (Zheng et al., 2020b)