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Triple-agonist: GLP-1 + GIP + glucagon receptors

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No validated human pharmacokinetics A human half-life, bioavailability, tissue distribution, metabolic pathway and exposure-response relationship have not been established through a published clinical programme

Mojca Jensterle Sever of the University of Ljubljana, is that obesity is still perceived as a lifestyle disease. But because obesity is a disease that requires clinical intervention to provide meaningful benefits, medications should be considered in certain individuals

10.1101/gad.1783809 Genes Dev