Interestingly, maternal dietary Se supplementation during gestation and lactation in goats increased testicular weight and volume, density of spermatogenic and Leydig cells, expression of enzymes in testosterone biosynthesis, androgenic receptor protein, and levels of testosterone in testicular tissue and serum (175)
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From the perspective of signaling pathway regulation, DHRS7 may exert diverse effects by modulating key signaling pathways, such as EGF/EGFR, TGF-, IL-4, PI3K/AKT, and MAPK