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doi: 10.3389/fphar.2014.00181 Received 31 May 2014 Accepted 16 July 2014 Published 11 August 2014 Volume 5 - 2014 Edited by Alfonso Pompella, Universit di Pisa, Italy Reviewed by Marc Diederich, Laboratoire de Biologie Molculaire et Cellulaire du Cancer, Hpital Kirchberg, Luxembourg

Each group included 217,302 patients

The percentage of subjects achieving weight loss (liraglutide 78% versus exenatide 76%) and overall weight loss (liraglutide 3.24 kg versus exenatide 2.87 kg, p = 0.22) was similar between groups

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In addition, in mice-cultured renal proximal tubule cells, NAM caused aninhibition of TGF-beta1, a master regulator of myofibroblast differentiation in fibrosis