The possible carcinogenic mechanisms involve an increase in oxidative stress, that may cause oxidative DNA damage, interfere with DNA repair systems, deregulate growth control mechanisms, and modify DNA methylation patterns ( Living in volcanic areas represents a further risk factor as some of the highest incidences of thyroid cancer are registered in volcanic regions ( Many heavy metals (As, Cd, Cr, Hg, and Pb) have never been tested yet as potential human thyroid carcinogens
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[7] [8] Nonetheless, monitoring recommendations were retained
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