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Increased nicotine self-administration following prenatal exposure in female rats

We have a great blog article on the differences between these types of nicotine but, to cut a long story short, there are several indicators that nic salt e-liquids may be more problematic than freebase e-liquids, one of which is the increased volume of flavourings used in nic salt e-liquids when it is known that flavourings are responsible for some of the volatile compounds produced by the vaping process

And indeed, the FDAs initiative appears to be highly focused on the role of menthol in drawing adolescents into a smoking habit