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Twin studies indicate that 4070% of the risk factors for nicotine dependence are inherited, as elaborated by Emory Universitys Emory News Center in Genetic Risks for Nicotine Dependence Span a Range of Traits and Diseases. Family history , where a history of substance use disorders, including tobacco use, escalates the likelihood of developing nicotine addiction

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Early signs of accidental nicotine exposure include quickened tachycardia, diaphoresis, nausea, and vomiting, late effects include hypotension, hypoventilation and other effects include coma, seizure, respiratory, cardiac arrest and death