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119,123 LC3Bs side chain undergoes structural rearrangemen to accommodate phosphorylation of FUNDC1, thereby serving as a sensor for the FUNDC1 phosphorylation

Chronic Obstructive Pulmonary Disease (COPD): Long-term tobacco smoking is the leading cause of COPD, a progressive and debilitating condition that includes chronic bronchitis and emphysema

So, although the style and details of the seals changed after the invention of writing, the significance of the seals did not

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